PhenoAge Biological Age Calculator (Levine)
The Levine 2018 model combines nine biomarkers and chronological age. PhenoAge is an age equivalent of population risk in the NHANES model, not organ age or individual life expectancy. The difference from age is subtraction, not an aging rate or the statistical PhenoAgeAccel residual.
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Calculation
Result
- Phenotypic age (PhenoAge)
- 31.7 years
- Difference from chronological age
- -8.3 years
Age equivalent of the estimated mortality risk in the NHANES model; not a measurement of organ age
PhenoAge minus age. An arithmetic difference, not a measured rate of aging.
Research model for ages 20–84. Acute illness changes biomarkers and the result. This is not a diagnosis, lifespan or proof of rejuvenation. CRP must be measured and positive; a result below the detection limit cannot be replaced with zero. Reference ranges are population benchmarks from the cited sources. Laboratories use their own ranges, and interpretation depends on clinical context: discuss the result with your physician.
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How it is calculated
The Levine 2018 model combines nine biomarkers and chronological age. PhenoAge is an age equivalent of population risk in the NHANES model, not organ age or individual life expectancy. The difference from age is subtraction, not an aging rate or the statistical PhenoAgeAccel residual.
Formula
xb = −19.907 − 0.0336·A + 0.0095·C + 0.1953·G + 0.0954·ln(CRP) − 0.012·L + 0.0268·M + 0.3306·R + 0.00188·P + 0.0554·W + 0.0804·a H = exp(xb) × (exp(120 × 0.0076927) − 1) / 0.0076927 PhenoAge = 141.50225 + ln(0.00553 × H) / 0.09165 A: albumin, g/L; C: creatinine, µmol/L; G: glucose, mmol/L; CRP: mg/dL (input mg/L ÷ 10); L: lymphocytes, %; M: MCV, fL; R: RDW, %; P: ALP, U/L; W: WBC, 10⁹/L; a: age, years.
Limits of the method
Research model for ages 20–84. Acute illness changes biomarkers and the result. This is not a diagnosis, lifespan or proof of rejuvenation. CRP must be measured and positive; a result below the detection limit cannot be replaced with zero.
Sources of the method
This calculation is for reference only and is not medical advice, a diagnosis or a prescription. If you have a medical condition, are pregnant, take medication or have any doubts, discuss the result with a physician or a qualified nutrition professional.
How to use the calculation
Enter the starting values
The Levine 2018 model combines nine biomarkers and chronological age. PhenoAge is an age equivalent of population risk in the NHANES model, not organ age or individual life expectancy. The difference from age is subtraction, not an aging rate or the statistical PhenoAgeAccel residual.
Adjust the parameters
xb = −19.907 − 0.0336·A + 0.0095·C + 0.1953·G + 0.0954·ln(CRP) − 0.012·L + 0.0268·M + 0.3306·R + 0.00188·P + 0.0554·W + 0.0804·a H = exp(xb) × (exp(120 × 0.0076927) − 1) / 0.0076927 PhenoAge = 141.50225 + ln(0.00553 × H) / 0.09165 A: albumin, g/L; C: creatinine, µmol/L; G: glucose, mmol/L; CRP: mg/dL (input mg/L ÷ 10); L: lymphocytes, %; M: MCV, fL; R: RDW, %; P: ALP, U/L; W: WBC, 10⁹/L; a: age, years.
Read the result
Research model for ages 20–84. Acute illness changes biomarkers and the result. This is not a diagnosis, lifespan or proof of rejuvenation. CRP must be measured and positive; a result below the detection limit cannot be replaced with zero.
Frequently asked questions
What does the calculation show?
The Levine 2018 model combines nine biomarkers and chronological age. PhenoAge is an age equivalent of population risk in the NHANES model, not organ age or individual life expectancy. The difference from age is subtraction, not an aging rate or the statistical PhenoAgeAccel residual.
What limitations apply?
Research model for ages 20–84. Acute illness changes biomarkers and the result. This is not a diagnosis, lifespan or proof of rejuvenation. CRP must be measured and positive; a result below the detection limit cannot be replaced with zero.
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What next
Formula breakdowns, biomarker reference ranges and nutrition articles with cited sources are in the NutriFit knowledge base.
Go to the knowledge base