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Albumin-Corrected Calcium Calculator

Corrected calcium = total calcium + 0.02 × (40 − albumin), with calcium in mmol/L and albumin in g/L. This is the simplified Payne equation.

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Calculation

Total calcium — Units
Albumin — Units

Result

Albumin-corrected calcium
2.28 mmol/L (9.1 mg/dL)

The correction does not measure ionized calcium and can misclassify results, particularly with low albumin. No universal calcium category is assigned.

Uncorrected total calcium
2.12 mmol/L
Albumin
32.0 g/L

The correction does not measure ionized calcium and can misclassify results, particularly with low albumin. No universal calcium category is assigned. Reference ranges are population benchmarks from the cited sources. Laboratories use their own ranges, and interpretation depends on clinical context: discuss the result with your physician.

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How it is calculated

Corrected calcium = total calcium + 0.02 × (40 − albumin), with calcium in mmol/L and albumin in g/L. This is the simplified Payne equation.

Formula

Corrected calcium = total calcium + 0.02 × (40 − albumin), with calcium in mmol/L and albumin in g/L. This is the simplified Payne equation. Ca: mg/dL × 0.2495 = mmol/L; mmol/L ÷ 0.2495 = mg/dL. Albumin: g/dL × 10 = g/L.

Limits of the method

The correction does not measure ionized calcium and can misclassify results, particularly with low albumin. No universal calcium category is assigned.

Sources of the method

  • Payne RB et al. Interpretation of serum calcium in patients with abnormal serum proteins. Br Med J, 1973
  • Ladenson JH et al. Failure of total calcium corrected for protein, albumin, and pH to correctly assess free calcium status. J Clin Endocrinol Metab, 1978
  • Desgagnés N et al. Use of Albumin-Adjusted Calcium Measurements in Clinical Practice. JAMA Netw Open, 2025

This calculation is for reference only and is not medical advice, a diagnosis or a prescription. If you have a medical condition, are pregnant, take medication or have any doubts, discuss the result with a physician or a qualified nutrition professional.

How to use the calculation

1

Enter the starting values

Corrected calcium = total calcium + 0.02 × (40 − albumin), with calcium in mmol/L and albumin in g/L. This is the simplified Payne equation.

2

Adjust the parameters

Corrected calcium = total calcium + 0.02 × (40 − albumin), with calcium in mmol/L and albumin in g/L. This is the simplified Payne equation. Ca: mg/dL × 0.2495 = mmol/L; mmol/L ÷ 0.2495 = mg/dL. Albumin: g/dL × 10 = g/L.

3

Read the result

The correction does not measure ionized calcium and can misclassify results, particularly with low albumin. No universal calcium category is assigned.

Frequently asked questions

What does the calculation show?

Corrected calcium = total calcium + 0.02 × (40 − albumin), with calcium in mmol/L and albumin in g/L. This is the simplified Payne equation.

What limitations apply?

The correction does not measure ionized calcium and can misclassify results, particularly with low albumin. No universal calcium category is assigned.

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Calculation assumptions

The correction does not measure ionized calcium and can misclassify results, particularly with low albumin. No universal calcium category is assigned.

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What next

Formula breakdowns, biomarker reference ranges and nutrition articles with cited sources are in the NutriFit knowledge base.

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