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Magnesium L-Threonate: Brain Access, Synaptic Function, and the Limits of Clinical Evidence

How magnesium L-threonate relates to brain magnesium, NMDA receptors, and synaptic plasticity. This review covers the compound’s chemistry, transport across barriers, animal and human memory studies, dosing, and safety without overstating the evidence.

October 8, 2026

Huperzine A: acetylcholinesterase and limits of neuroprotection

A detailed account of reversible AChE inhibition, pharmacokinetics, NMDA, mitochondria, Nrf2 and APP. Dementia trials are distinguished from cell and animal findings, with safety, interactions and practical assessment of memory complaints.

October 3, 2026

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Magnesium L-Threonate: Brain Access, Synaptic Function, and the Limits of Clinical Evidence

Huperzine A: acetylcholinesterase and limits of neuroprotection