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Knowledge · General

Xenohormesis: plant stress, cellular adaptation and the limits of longevity evidence

How plant defense chemistry interacts with Nrf2, AMPK, sirtuins and autophagy. Biosynthesis, agroecology, metabolites, pharmacokinetics and the limits of translating mechanisms into human health and lifespan.

October 8, 2026
Knowledge · Supplements

Chinese magnolia vine: schisandrins, Hsp70, and the limits of its effects on fatigue

From berry composition and lignan stereochemistry to chaperones, mitochondrial glutathione, Nrf2, and neuroendocrine hypotheses: human research, standardization, and drug interactions.

October 8, 2026
Knowledge · Supplements

Molecular hydrogen: redox mechanisms, delivery and the limits of clinical evidence

H₂ biophysics, Henry's law, competition in radical reactions, Nrf2/Keap1, inflammatory and mitochondrial pathways, and early clinical trials including the negative primary endpoint of HYBRID II.

October 8, 2026